- Born on October 26, 1431 in Ferrara
- Deceased on January 25, 1505, at the age of 73 years
Parents
- Niccolò III d'Este (1383 - 1441), signore di Modena
- Ricciarda di Saluzzo ( - 1474)
Family
- Relationship with Lodovica Condulmero, issuing
Lucrezia (1469 - 1518)
- Married on June 22, 1473, with Eleonora d'Aragona (1450 - 1493), issuing
- Isabella (1474 - 1539)
- Beatrice (1475 - 1497)
- Alfonso I (1476 - 1534)
- Ferdinando (1477 - 1540)
- Ippolito (1479 - 1520)
- Sigismondo (1480 - 1524)
- Relationship with Isabella Arduino, issuing
- Giulio (1478 - 1561)