Parents
- René de Birague, chancelier de France, cardinal
- Valentine Balbiano (1518 - 1582)
Family
- Married on April 15, 1561, with Imbert de La Platière (1516 - 1567), seigneur de Bourdillon, maréchal de France
- Married in 1571, with Jean de Laval-Loué (1542 - 1578), chevalier, marquis de Nesle, capitaine de cinquante hommes d'armes des ordonnances, issuing
- Married on February 8, 1584, with Jacques d'Amboise ( - 1587), comte d'Aubijoux